Possible Effect of Persimmon (Diospyros kaki) Fruits in Streptozotocin-Induced Diabetic Rats

نوع المستند : بحوث علمية محکمة

المؤلفون

1 Faculty of Agriculture, Alexandria University

2 Dairy Science Department, Food Science and Technology Institute, Research Center Institute, Giza

المستخلص

Abstract
The effects of different concentrations (2, 4 and 6%) of persimmon fruits (Diospyros kaki) powders on diabetic rats was evaluated. Thirty  Albino rats weating 140±10 g were used in this study and divided into 5 groups, each group contain 6 rats. Rats were treated by streptozotocin (40mg/kg B.W) to induced diabetic. Results showed that the highest body weight gain, feed intake and feed efficiency ratio recorded for 6 % persimmon fruits, while the lowest recorded for 2 % persimmon fruits with no significant difference.Rat groups fed on 6% persimmon fruit recorded the highest liver, kidney and spleen weight. Rats fed on 6 % persimmon fruit recorded the lowest glucose level with a significant difference being, 97.53 mg/dl. The lower ALT, AST and ALP liver enzyme of treated group which recorded for group fed on 6 % persimmon fruits, but the highest value recorded for group fed on 2 % persimmon fruits with a significant difference. Lowest value of triglyceride and cholesterol recorded for group fed on 6 % persimmon fruit. The highest HDL-c of treated group recorded for group fed on 6 % persimmon fruits. While, the highest LDL-c and VLDL-c of treated group recorded for rats fed on 2 % persimmon fruits. The highest urea and uric acid levels of treated group which recorded for group fed on 4 % persimmon fruits. While, the lowest creatinine level of treated group which recorded for group fed on 6 % persimmon fruits. As conclusion, 6.0 % % persimmon fruits as powder recorded the best levels for improvement glucose levels, lipid profile, liver functions and kidney functions. Therefore, 6.0 % % persimmon fruits as powder could be used in our drinks and many dishes.

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